Abstract
A reddish glow localized within the iris was observed in the photographs of some individuals in the dark using an electric-arc flash. On repeated exposure and reprints of the same individuals to photography under similar conditions, the red glow persisted. Studies were under taken to analyze thein vitro effect of cupric ions on the activity of serum tyrosinase. A significant increase in the activity of tyrosinase was observed in the affected individuals as compared to the controls when cupric ion was supplementedin vitro. Studies also confirmed the inhibitory effect of benzoic acid on serum tyrosinase activityin vitro. Our preliminary studies have shown a significant decrease (p<0.001) in tyrosinase activity in the serum of the photosensitive individuals compared to controls which is consistent with the observed red glow on the photographic prints and reprints.
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