Year-end Sale % OFF 
Abstract
A first cousin marriage family with three children was studied. One sibling (AW) was homozygous for W32.W10. When used as stimulator in one way MLC, AW elicited a very low response in family members possessing this haplotype. Serologically identical sibling and father combination showed bidirectional non-stimulation in one way MLC. Therefore, AW is assumed to be homozygous not only for SD antigens, but also for LD determinants which we call LD W10a. Among the 43 unrelated individuals tested with AW, an association between LD W10a and W10 antigen of the second HL-A locus was observed. Of 12 W10 positive individuals tested, five carry this allele as compared to one out of 31 W10 negative individuals. The data suggest a strong linkage disequilibrium between the FOUR locus determinant W10 and LD determinant LD W10a.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
