Abstract
SummaryBackgroundThe aim of this study was to present a practical concept focusing on typical aspects of regular physical activity, exercise and physical modalities for patients suffering from metastatic bone disease or multiple myeloma.MethodsA narrative review of the relevant scientific literature and presentation of clinical experiences.ResultsIn cancer patients with metastatic bone disease or multiple myeloma, pain is treated in an interdisciplinary and multimodal setting by using medication, radiotherapy and physical medical modalities (e.g. transcutaneous electrical nerve stimulation); however, modalities increasing local blood flow, such as ultrasound therapy, thermotherapy, massage, various electrotherapy options, are not performed at the site of the tumor. For physical activity and exercise, a suitable indication of the static and dynamic capacity of the affected skeletal structures is essential. This process includes strategies to maintain and improve mobility and independence. Individually tailored and adapted physical activity and exercise concepts (programs) within a multidisciplinary and interdisciplinary setting (tumor board) are used to manage the condition and bone load-bearing capacity of the patient. Typical clinical features and complications, such as pathological fractures in patients suffering from metastatic bone disease and additionally hypercalcemia, monoclonal gammopathy with bone marrow aplasia and risk of renal failure in patients with multiple myeloma have to be considered when planning supportive strategies and rehabilitation.ConclusionIn order to ensure the safety and effectiveness of regular physical activity, exercise, and physical modalities in patients with metastatic bone disease or multiple myeloma, typical contraindications and considerations should be noted.
Highlights
Modern cancer and hemato-oncological treatment results in improvement of survival of patients suffering from metastatic cancer or multiple myeloma [1,2,3,4,5,6]
The aim of the present study was to present a concept of typical aspects of regular physical activity, exercise and physical modalities for cancer patients suffering from metastatic bone disease or multiple myeloma
This narrative review could provide important information for the treatment and rehabilitation of patients suffering from metastatic bone disease and in multiple myeloma patients, even in challenging cases
Summary
Modern cancer and hemato-oncological treatment results in improvement of survival of patients suffering from metastatic cancer or multiple myeloma [1,2,3,4,5,6]. Regular physical activity is an active option, which has been shown to be an important component in the treatment and rehabilitation of cancer patients and has been described to improve functional health of cancer patients with benefits for physical performance, mental health, quality of life, participation and in some types of cancer survival. Despite the known benefits of regular physical activity, exercise and other physical modalities for patients with cancer, prescription and performance of these therapies in patients with metastatic disease or multiple myeloma is challenging [7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24]. There is often uncertainty in prescription and performance of such supportive and/or rehabilitation therapies, especially due to the fear of possible pathological fractures and spinal cord compression in metastatic cancer or multiple myeloma
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