Abstract
Background and Aims : Altered vascular tone in prolonged hyperglycemia is mainly due to endothelial impairment and changes in the functionality of smooth muscle potassium channels (SMPC). However, the fact that resveratrol (RSV) is able to cause relaxation of those vessels, poses intriguing lights in the cellular target sites at which it acts in pathological conditions. Our aim was to give an overview at the types of SMPK involved in the mechanism of RSV action in diabetic patients.
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