Abstract
AbstractType I plasminogen deficiency is a rare autosomal recessive systemic disorder. It usually starts in infancy and is clinically characterized by chronic mucosal pseudomembranous lesions which...
Highlights
Type I plasminogen deficiency is an autosomal recessive disorder
There are two types of plasminogen deficiency: Type I is characterized by decreased plasminogen activity, plasminogen antigen levels and clinical symptoms
Type I plasminogen deficiency is a very rare autosomal recessive disease caused by plasminogen gene (PLG) mutations
Summary
Type I plasminogen deficiency is an autosomal recessive disorder. It was first described in 1847 and first detailed histological description was reported in 1924 (Schuster & Seregard, 2003). In 1997, Schuster et al demonstrated plasminogen (PLG) gene mutations for the cause of the disease
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