Type-2 Diabetes Mellitus with Neuropathy: “Clinical Presentation and Nerve Conduction Study Findings”

Abstract

Background: Diabetes mellitus (DM) is one of the chronic diseases all over the world. The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia with disturbance of carbohydrate, fat, and protein metabolism resulting from defects in insulin secretion, insulin action or both with an increased risk of neuropathy and other complications. Objective: To describe the clinical features and findings of nerve conduction study among the patients presented with diabetic neuropathy. Methods and Material: The study was conducted at the outpatient department of Uttara Crescent Hospital, Uttara, Dhaka, Bangladesh. Total 83 patients presented with a history of diabetes for 20 years and above and having features of neuropathy are included in this study. Patients who are suspected having neuropathy due to any other known cause were excluded from this study. Detail history regarding complaints of neuropathy was taken. History of symptoms like paraesthesia, tingling sensation, burning feet, hyperaesthesia, foot ulcer, history of weakness and gait abnormality was noted. Complete nervous system examination was performed and nerve conduction study was done. Results: Among the total 83 presented with neuropathy; the mean (±SD) age (Years) was 51.80 ((±10.24) with a range of 35-60 years (Fig-1). Out of total 83 patients, 60.24% (n=50) were male and 39.76% (32) were female. In our study we found that out of 83 patients 74 patients (89%) presented with tingling sensation at limbs, 52 patients (62.65%) had burning feet, 47 patients (56.63%) had diminished or loss of vibration sense, and 34 patients (41%) patients have diminished light touch. Above finding suggested that most patients presented with sensory symptoms. Out of 83 patients 42 patients (50.60%) had diminished ankle jerk and only 6 patients presented with foot ulcers. In this study out of 83 patients ...............