Abstract
Eosinophils are commonly associated with Th2-type inflammation as occurs in allergic diseases such as asthma. However, eosinophils are, also, present in vivo in Th1-type environments found in translational models of infection, cancer, or transplant. Little is known regarding type 2 and type 1 immune phenotypes of mouse and human eosinophils. The goal was to compare mouse and human eosinophil immune phenotypes following exposure to Th2 and Th1 cytokines.
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