Two-Stage Liver and Tumor Segmentation Algorithm Based on Convolutional Neural Network.

Abstract

The liver is an essential metabolic organ of the human body, and malignant liver tumors seriously affect and threaten human life. The segmentation algorithm for liver and liver tumors is one of the essential branches of computer-aided diagnosis. This paper proposed a two-stage liver and tumor segmentation algorithm based on the convolutional neural network (CNN). In the present study, we used two stages to segment the liver and tumors: liver localization and tumor segmentation. In the liver localization stage, the network segments the liver region, adopts the encoding–decoding structure and long-distance feature fusion operation, and utilizes the shallow features’ spatial information to improve liver identification. In the tumor segmentation stage, based on the liver segmentation results of the first two steps, a CNN model was designed to accurately identify the liver tumors by using the 2D image features and 3D spatial features of the CT image slices. At the same time, we use the attention mechanism to improve the segmentation performance of small liver tumors. The proposed algorithm was tested on the public data set Liver Tumor Segmentation Challenge (LiTS). The Dice coefficient of liver segmentation was 0.967, and the Dice coefficient of tumor segmentation was 0.725. The proposed algorithm can accurately segment the liver and liver tumors in CT images. Compared with other state-of-the-art algorithms, the segmentation results of the proposed algorithm rank the highest in the Dice coefficient.