Abstract

Melanoma is a skin disease with a high fatality rate. Early diagnosis of melanoma can effectively increase the survival rate of patients. There are three types of dermoscopy images, malignant melanoma, benign nevis, and seborrheic keratosis, so using dermoscopy images to classify melanoma is an indispensable task in diagnosis. However, early melanoma classification works can only use the low-level information of images, so the melanoma cannot be classified efficiently; the recent deep learning methods mainly depend on a single network, although it can extract high-level features, the poor scale and type of the features limited the results of the classification. Therefore, we need an automatic classification method for melanoma, which can make full use of the rich and deep feature information of images for classification. In this study, we propose an ensemble method that can integrate different types of classification networks for melanoma classification. Specifically, we first use U-net to segment the lesion area of images to generate a lesion mask, thus resize images to focus on the lesion; then, we use five excellent classification models to classify dermoscopy images, and adding squeeze-excitation block (SE block) to models to emphasize the more informative features; finally, we use our proposed new ensemble network to integrate five different classification results. The experimental results prove the validity of our results. We test our method on the ISIC 2017 challenge dataset and obtain excellent results on multiple metrics; especially, we get 0.909 on accuracy. Our classification framework can provide an efficient and accurate way for melanoma classification using dermoscopy images, laying the foundation for early diagnosis and later treatment of melanoma.

Highlights

  • Skin cancer is a major public health problem, with more than 5 million new cases diagnosed annually in the United States (Siegel et al, 2016; Codella et al, 2018)

  • We propose a novel two-stage ensemble method based on deep convolutional neural networks

  • The images in the dataset are classified as three classes: benign nevi (BN), seborrheic keratosis (SK), or melanoma (MM)

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Summary

Introduction

Skin cancer is a major public health problem, with more than 5 million new cases diagnosed annually in the United States (Siegel et al, 2016; Codella et al, 2018). Dermoscopy images can greatly improve the accuracy of diagnosis (Kittler et al, 2002; Codella et al, 2018). Dermatologists usually use “ABCD” rule to evaluate skin lesions (Stolz, 1994; Moura et al, 2019). This rule analyzes asymmetry, boundary irregularities, color variations, and structures of lesions (Xie et al, 2016). The differentiation of skin lesions by dermatologists from dermoscopy images is often time consuming and subjective, and the diagnostic accuracy depends largely on the professional level, so inexperienced dermatologists may not be able to make accurate judgments. We urgently need an automatic recognition method that is non-subjective and can assist dermatologists to make more accurate diagnosis

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