Abstract

DNA strand displacement has been widely used in designing the molecular logic circuit, nanomedicine and molecular automata and so on. In this article, the two-digit full subtractor is designed by DNA strand displacement reaction and has been verified by the simulation of DNA strand displacement. The accuracy of simulation results is further confirmed that DNA strand displacement is a valid method for the research of logical bio-chemical circuit. The multi-digit full subtractor could be used in biological computer in the future.

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