Abstract

1918 Spanish flu and COVID-19 can be considered as most hazardous pandemics earth has ever witnessed. They are results of what mayhems an organism not even visible with naked eye can cause. Causative agent for both the diseases is a virus but, they are not same. 1918 Spanish flu gave major indications that it has the existence of the new strain of flu and lasted for longer duration affecting lives in various ways. COVID-19 is again an indication of another emerging worst pandemic. Here, we have reviewed the overall factors that contributed to the severity of these two pandemics and comparison of the same. The main motive of this paper is to put together, compare and analyze versatility of both the pandemics and to discuss implications of the same.

Highlights

  • History suggests that, pandemics have caused widespread illness infecting millions of people worldwide, causing thousands of deaths

  • This review aims at gathering the essential information and to summarize findings on origin, epidemiology, clinical features, treatments and comparisons between Spanish flu and COVID-19

  • In attempts to control the spread of influenza virus, physicians developed and recommended non-standardized vaccines, as the medical community believed that influenza pandemic was caused by bacillus Haemophilus influenzae(named later), these vaccines were primarily recommended for protection against Pfeiffer’s bacillus[20]

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Summary

Introduction

Pandemics have caused widespread illness infecting millions of people worldwide, causing thousands of deaths. All the three criteria mentioned above, for a virus to cause pandemic, are fulfilled by H1N1 virus and novel corona virus responsible for causing 1918 influenza and COVID-19 pandemic respectively [3]. Both the 1918 influenza which is referred as mother of all pandemics by Taubenberger and Morens [4] as well as COVID-19 referred as “once in a century health crisis”, by WHO [5], has led to ruinous and scarring impacts on health and lives of people with the outcomes capable of remaining irreversible for a decennary or more. This review aims at gathering the essential information and to summarize findings on origin, epidemiology, clinical features, treatments and comparisons between Spanish flu and COVID-19

The 1918 Spanish flu
Origin and Epidemiology
Virology
Transmission
Diagnosis
Clinical Manifestations
Treatment
Vaccines
Post-Influenza Manifestations
COVID-19
Post-COVID Manifestations
Infectious agent
Cell receptor
Symptoms
Clinical
Conclusion
Full Text
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