Abstract
Two migrated ursane skeleton triterpenoids, one is D:B-friedoursane-3α,16α-dihydroxy-7α,8α-epoxy-5(10)-ene, named petatrichol A ( 1) and the other one represents a novel triterpenoid carbon framework, named petatrichol B ( 2), along with 10 known compounds were isolated from the rhizome of Petasites tricholobus. Their structures were elucidated on the basis of spectroscopic methods (IR, EIMS, HRMS, 1D and 2D NMR). The triterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 1 and 2 exhibited significant antibacterial activity against B. subtilis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have