Abstract
BackgroundOutcome data on two-stage revision surgery for deep infection after septic hip arthritis are limited and inconsistent. This study presents the medium-term results of a new, standardized two-stage arthroplasty with preformed hip spacers and cementless implants in a consecutive series of adult patients with septic arthritis of the hip treated according to a same protocol.MethodsNineteen patients (20 hips) were enrolled in this prospective, non-randomized cohort study between 2000 and 2008. The first stage comprised femoral head resection, debridement, and insertion of a preformed, commercially available, antibiotic-loaded cement hip spacer. After eradication of infection, a cementless total hip arthroplasty was implanted in the second stage. Patients were assessed for infection recurrence, pain (visual analog scale [VAS]) and hip joint function (Harris Hip score).ResultsThe mean time between first diagnosis of infection and revision surgery was 5.8 ± 9.0 months; the average duration of follow up was 56.6 (range, 24 - 104) months; all 20 hips were successfully converted to prosthesis an average 22 ± 5.1 weeks after spacer implantation. Reinfection after total hip joint replacement occurred in 1 patient. The mean VAS pain score improved from 48 (range, 35 - 84) pre-operatively to 18 (range, 0 - 38) prior to spacer removal and to 8 (range, 0 - 15) at the last follow-up assessment after prosthesis implantation. The average Harris Hip score improved from 27.5 before surgery to 61.8 between the two stages to 92.3 at the final follow-up assessment.ConclusionsSatisfactory outcomes can be obtained with two-stage revision hip arthroplasty using preformed spacers and cementless implants for prosthetic hip joint infections of various etiologies.
Highlights
Outcome data on two-stage revision surgery for deep infection after septic hip arthritis are limited and inconsistent
The cohort consisted of consecutive patients referred to our departments from 2000 to 2008 for chronic deep hip joint infection
In 11 patients, joint aspiration was performed prior to surgery at our institution; none of these patients presented with draining fistulas and previous cultures were either not available or negative
Summary
Outcome data on two-stage revision surgery for deep infection after septic hip arthritis are limited and inconsistent. This study presents the medium-term results of a new, standardized two-stage arthroplasty with preformed hip spacers and cementless implants in a consecutive series of adult patients with septic arthritis of the hip treated according to a same protocol. Failure rates after debridement increase rapidly in the first days after onset of symptoms [1] and more radical surgery may be required as joint. Two-stage total hip arthroplasty (THA) with an interval antibiotic-loaded polymethylmetacrylate spacer has been recently proposed to clear infection and improve hip function after septic hip arthritis [7,8,9]. In a recent case report, Regis et al [10] described successful two-stage hip reconstruction after septic arthritis with a commercially produced, preformed antibiotic-impregnated cement spacer
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