Abstract
BackgroundTwo-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The aim of the present study was to evaluate clinical and functional outcomes with the Modular Universal Tumor And Revision System (MUTARS) RS stem in patients undergoing two-stage revisions.MethodsThe functional and clinical outcomes for 43 patients who had undergone two-stage revision procedures for PJI were analyzed in a retrospective study. The minimum follow-up period was 24 months. Shorter follow-up periods were only observed when there were complications such as loosening or recurrent infection. The mean follow-up period was 3.86 years (range 7 months to 11.6 years).ResultsThe success rate with infection control for PJI was 93%. Reinfection occurred in four cases (7%). The risk of reinfection after MRSA infection was 20.5 times greater (P >0.01) than with sensitive or unknown bacteria. Two aseptic loosening occurred after 7 and 20 months. The average Harris Hip Score was 80 (range 62–93).ConclusionThis retrospective study showed a 93% rate of eradication using specific antibiotic therapy. With the modular MUTARS RS stem, there was a low rate of aseptic loosening of 4.6%. MRSA infection was identified as a risk factor for reinfection. The two-stage procedure with modular cementless implants used is therefore appropriate for treating periprosthetic infections associated with hip endoprostheses.Electronic supplementary materialThe online version of this article (doi:10.1186/1471-2474-15-398) contains supplementary material, which is available to authorized users.
Highlights
Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection
The cause of persisting infection was a nonsensitive spacer in a patient with methicillin-resistant S. aureus (MRSA) in one case, persistent fistula in two cases, and persistently high C-reactive protein levels in one case
The present study focuses on the reinfection rate and early loosening of the Modular Universal Tumor And Revision System (MUTARS) RS stem (Implantcast Ltd., Buxtehude, Germany)
Summary
Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The number of total hip arthroplasties (THA) carried out in Germany has increased in recent years up to 160,000 annually [1]. The current rate of prosthetic joint infection (PJI) in Europe and the United States is around 0.6–1.0% for THA [1,2,3]. This indicates that the number of THA increasing, and the absolute numbers of infections. Treatment for PJI depends on the duration of symptoms. With symptoms for less than 4 weeks, can be treated with local debridement and
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