Abstract

Two severe familial cases of botulism were reported to the health authorities in Brittany, north-west France, on 11 August 2008. An investigation was undertaken to identify additional cases, the vehicle of transmission, and to put in place adapted control measures.

Highlights

  • Serum samples from the cases and samples recovered from the food investigation were analysed by the National reference laboratory (NRL) for anaerobic bacteria and botulism at the Pasteur Institute, Paris

  • The presence of botulinum toxin was confirmed by intraperiteonal administration of patient serum to mice, and the toxin type was ascertained by the specific neutralisation technique

  • A trivalent antitoxin was administered to the patients on 13 August. This antitoxin was imported from a commercial laboratory in Germany as botulism antitoxins are not commercially available in France

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Summary

Rapid communications

Two s eve r e cas e s o f botu l i s m asso c iate d w ith industrial ly producedchickenenchiladas , France , August 2008. Two severe familial cases of botulism were reported to the health authorities in Brittany, north-west France, on 11 August 2008. An investigation was undertaken to identify additional cases, the vehicle of transmission, and to put in place adapted control measures

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