Abstract
Two pairs of phenylpropanoid enantiomers, (+)-(7S,8S)-alatusol D (1a), (−)-(7R,8R)-alatusol D (1b), (−)-(7S,8R)-alatusol D (2a) and (+)-(7R,8S)-alatusol D (2b) were isolated from the leaves of Eucommia ulmoides Oliver. Among them, 1a and 2b were firstly obtained by chiral enantiomeric resolution. Their structures were elucidated based on extensive spectroscopic analysis and the induced CD (ICD) spectrum caused by adding Mo2(AcO)4 in DMSO. All compounds were tested on Hep G2 tumor cell lines. However, none of the compounds showed potential cytotoxic activity against Hep G2 in vitro.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have