Abstract
Two new withanolides named physaminilides L (1) and M (2), together with four known ones (3–6) were isolated from the Physalis minima L. The structures were established by analysis of the HR ESIMS, IR and NMR spectroscopic data. The absolute configurations were determined through NOESY and ECD spectra. For compounds 1–5 assayed at 20 µM and compound 6 at 10 µM, inhibition rates of hepatic fibrosis were 22.19%, 15.29%, 37.07%, 9.27%, 12.45%, and 37.03%, respectively.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have