Abstract

Two new tetralone derivatives named xylariol A ( 1) and B ( 2) were isolated from the EtOAc extract of the culture broth of Xylaria hypoxylon AT-028 (Xylariaceae), and their structures were elucidated by MS, IR, 1D- and 2D-NMR spectra, and by X-ray diffraction analysis. 1 and 2 showed moderate cytotoxic activities against Hep G2 cells in the in vitro cytotoxic assay with IC 50 values of 22.3 and 21.2 μg/mL, respectively.

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