Abstract
Two new hydroxylated ent-kauranoic acids, pterisolic acid G (1) and pterisolic acid H (3), together with five known ent-kaurane-type diterpenoids (2 and 4–7) were isolated from the whole plant of Pteris semipinnata L. The structures of compounds 1–3 were elucidated on the basis of HR-MS, 1D and 2D NMR analysis, and the absolute configuration of compounds 1 and 2 were determined by the results of single crystal X-ray diffraction experiment. Compounds 1–4 and 6–7 were evaluated in vitro cytotoxicity against the A549, CT26.WT, and Hep G2 cells, and compounds 4 and 6 possessed varying degrees of activity.
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