Abstract
• Two unknown compounds were isolated from Dianella ensifo lia (L.) DC. • The structures for two new compounds were elucidated by spectroscopic analyses. • Compound 2 exhibited inhibitory effects against PTP-1B. The Dianella genus includes approximately 20 species in all over the world. So far, only the chemical constituents of the lipophilic extract from Dianella ensifolia have been investigated. However, there have been no reports of its aqueous extract. In this article, two previously undescribed glucopyranosides, methyl 2-methoxyl-6-methyl benzoate-4-O- β - D -glucopyranoside ( 1 ) and methyl 2-hydroxy-3,6-dimethyl benzoate-4-O- β - d -glucopyranosyl-(1→6)- β - d -glucopyranoside ( 2 ), were isolated from the aqueous extract of D. ensifolia . Their structures were elucidated by comprehensive spectral measurements and comparisons with data reported in the literature. Compound 2 exhibited inhibitory effects against PTP-1B with an IC 50 value of 12.88 ± 0.87 μM.
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