Abstract
In this work, two new flavonoids, oblongifolioside A (1) and oblongifolioside B (2), along with eight known compounds (3–10), are isolated from the leaves of Baccharis oblongifolia (Asteraceae). The new structures are established through spectroscopic data and the known compounds are identified by comparison with data reported in the literature. The compounds (1–10) are evaluated in relation to their antiradical properties. Compounds 1 and 2 are found to exhibit high antiradical activity compared to their respective non-acylated flavonoids.
Highlights
Baccharis L. (Astereae, Asteraceae) is a large New World genus comprising between 354 and 500 species [1,2]
90% of Baccharis species are found in South America and distributed mainly in the warm temperate and tropical regions of Argentina, Brazil, Chile, Colombia, and Mexico
Some Baccharis species are used in folk medicine, including for spasmolytic, diuretic, and analgesic purposes and for the treatment of ulcers, fever, gastrointestinal illnesses, diabetes, and microbial infections [4,5,6]
Summary
Baccharis L. (Astereae, Asteraceae) is a large New World genus comprising between 354 and 500 species [1,2]. Previous phytochemical studies of this genus have reported several classes of natural products, such as chlorogenic acid derivatives [4,7,8,9,10], terpenoids [11,12,13,14,15,16,17,18,19,20,21,22], especially diterpenes with dozens of isolated compounds from Baccharis [4,5,17,18,19,20,21,22], and flavonoids from flavone, flavanone, and flavonol types [4,5,21,22,23,24,25,26] It has been described as having diverse biological activities including antimicrobial [4,5,6,14,15], antiviral [4,5,6], antiprotozoal [9,24,25], anti-inflammatory [10,13], cytotoxic [4,5,6,23], and antioxidant [7,13,14,15,22,23], as well as antimutagenic and chemopreventive effects [4,5,6].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
