Abstract

Two new kaurane diterpenoids, 3 alpha,16 beta-17-trihydroxy-ent-kaurane 3-O-beta-D-glucopyranoside and 2 beta,3 alpha-dihydroxy-ent-kaur-15-en-17-oic acid 3-O-beta-D-glucopyranoside, were isolated from the bark of Albizia mollis (Wall.) Boiv. The structures of two new compounds were elucidated by extensive 1D- and 2D-NMR spectroscopic methods in combination with MS experiments.

Highlights

  • Two new kaurane diterpenoids, 3α, 16β, 17-trihydroxy-ent-kaurane 3-O-β-D-glucopyranoside and 2β,3α-dihydroxy-ent-kaur-15-en-17-oic acid 3-O-β-D-glucopyranoside, were isolated from the bark of Albizia mollis (Wall.) Boiv

  • Plant species of Albizia are known for their traditional medicinal uses as medicaments of mind unrest, insomnia, physique damage, carbuncle gall in many parts of tropic zone

  • In China, Albizia mollis, popularly named “maoyehehuan” is one of representative plant species of this family. This plant is well known for its sedative and sleeping pill properties.[1]

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Summary

Short Report

Two New ent-Kaurane Diterpenoids from Albizia mollis (Wall.) Boiv. Dois novos diterpenos com esqueleto caurano, 3a,16b-17-tri-hidróxi-ent-caurano 3-O-b-Dglucopiranosídeo e ácido 2b,3a-di-hidróxi-ent-caur-15-eno-17-óico 3-O-b-D-glucopiranosídeo, foram isolados das cascas de Albizia mollis (Wall.) Boiv. 3α, 16β, 17-trihydroxy-ent-kaurane 3-O-β-D-glucopyranoside and 2β,3α-dihydroxy-ent-kaur-15-en-17-oic acid 3-O-β-D-glucopyranoside, were isolated from the bark of Albizia mollis (Wall.) Boiv. In China, Albizia mollis, popularly named “maoyehehuan” is one of representative plant species of this family. This report describes the isolation and structural elucidation of two new ent-kaurane diterpenoids named mollissides A (1) and B (2)

Results and Discussion
HH ROESY
Plant material
Extraction and isolation
Mollisside B
Full Text
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