Abstract

A new cassane diterpenoid, caesappine A (1), and a new natural cassane diterpenoid, caesappine B (2) were isolated from the seeds of Caesalpinia sappan. The new structures of compounds 1 and 2 were elucidated by analysing their 1D NMR, 2D NMR and HR-ESI-MS spectra. Compounds 1 and 2 were evaluated for the cytotoxic activities on Hela and HepG-2 human cancer cell lines.

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