Abstract
In our natural product screening program from marine fungi, two new aromatic polyketides karimunones A (1) and B (2) and five known compounds (3–7) were isolated from sponge-associated Fusarium sp. KJMT.FP.4.3 which was collected from an Indonesian sponge Xestospongia sp. The structures of these compounds were determined by the analysis of NMR and MS spectroscopic data. The NMR assignment of 1 was assisted by DFT-based theoretical chemical shift calculation. Compound 2 showed antibacterial activity against multidrug resistant Salmonella enterica ser. Typhi with a MIC of 125 µg/mL while 1 was not active.
Highlights
Configuration of Terminal and Spiroepoxides by Computational Methods
Data are More Discriminating than Carbon", The Journal of Organic Chemistry, 2014
43 Pelletier, J.C.. "2-Phenyl-4piperazinylbenzimidazoles: Orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor", Bioorganic & Medicinal
Summary
1 "Biosynthesis of Indocarbazostatin B, Incorporation of D-[U-13C] Glucose and L-[213C] Tryptophan", The Journal of Antibiotics, 12/2005. 1502 and Endophytic Fungus AF-04 ", Journal of Agricultural and Food Chemistry, 2019. " New leishmanicidal physalins from ", Natural Product. 13 Shiqiong Lu, Weibo Sun, Jiajia Meng, Ali Wang et al " Bioactive Bis-naphtho-γ-pyrones from Rice False Smut Pathogen ", Journal of Agricultural and Food Chemistry, 2015. " Highly Oxygenated -PimaraneType Diterpenoids from the Chinese Liverwort and Their Allelopathic Activities ", Journal of Natural Products, 2013. 17 He, Jun-Wei, Zhen-Qiang Mu, Hao Gao, GuoDong Chen, Qin Zhao, Dan Hu, Jing-Zu Sun, Xiao-Xia Li, Yan Li, Xing-Zhong Liu, and XinSheng Yao. Their Activity as Inhibitors of Human Lactate Dehydrogenase ", Journal of Natural Products, 2017. 28 Peng Sun, Qing Yu, Jiao Li, Raffaele Riccio et al " Bissubvilides A and B, Cembrane– Capnosane Heterodimers from the Soft Coral ", Journal of Natural Products, 2016. Ohnishi. " Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
