Abstract
Two new anti-tobacco mosaic virus (anti-TMV) xanthones, 4,7-dimethoxy-5-hydroxymethyl-1-methylxanthone (1) and 7-hydroxy-5-hydroxymethyl-4-methoxy-1-methylxanthone (2), were isolated from the whole plants of Comastoma pedunculatum. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 48.5 and 63.6%, respectively. These rates are higher than that of positive control.
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