Two new alkaloids isolated from Dictamnus dasycarpus Turcz

Abstract

Two new quinoline alkaloids (1–2) together with twenty-two known alkaloids (3–24) were isolated and identified from Dictamnus dasycarpus Turcz. Compounds 6–7, 9, 11, 15–16, 19 and 24 were isolated from D. dasycarpus for the first time. The structures of all compounds were characterised by spectroscopic methods (1D, 2D NMR and HRESIMS). The anti-proliferative activity was mediated by the arrest of three human cancer cell lines (SW982, HepG2 and A549) of all the compounds that were evaluated by CCK-8 assay.