Abstract
Two new alkaloids, aspastipuline (1) and 5-hydroxyaspastipuline (2) were isolated from Asparagus stipularis Forssk. roots. Their structures were elucidated by spectroscopic techniques (1D and 2D NMR, HREIMS). The absolute structure of 2 was established by single-crystal X-ray diffraction analysis. Aspastipuline exhibited a moderate antiproliferative activity against the human mammary gland adenocarcinoma cell line MCF-7.
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