Abstract
Aim: Barrisal isaherbal medication used in Pakistan for hepatic and spleen ailments. It is composed of Aloevera. The present study was aimed to evaluate the teratogenic effects of barrisal in two generations of rats. Study Design: Two generation teratogenic activity Place and Duration of Study:Dr. Hafiz Muhammad Ilyas Institute of Pharmacology and Herbal Sciences (Dr. HMIIPHS)Hamdard University, Karachi, Pakistan ,between June 2002 and July 2004. Methodol ogy: In first phase two groups offemale rats (10 rats each group) were used. One group received normal saline (ascontrol group).Group II were treated with a single oral doseof10ml/kg barrisal (10 female rats) during the whole period of gestation till the
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