Abstract
Two ellagic acid glycosides were isolated by bioassay-guided fractionation from the antimicrobial ethyl acetate fraction of the ethanol extract from Gleditsia sinensis spines, and identified as 3-O-methylellagic acid-4′-(5″-acetyl)-α-L-arabinofuranoside (1) and 3-O-methylellagic acid-4′-O-α-L-rhamnopyranoside (2). Both compounds were isolated from this plant species for the first time, and 1 is a new compound. The two compounds showed significant antifungal activity against the spore germination of rice blast fungus Magnaporthe grisea, with an IC50 value of 13.56 µg mL−1 for 1 and 16.14 µg mL−1 for 2.
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