Abstract

Two Dimensional Speckle Tracking Echocardiography Assessment of Left Ventricular Remodeling in Patients after Myocardial Infarction

Highlights

  • Improvement in the early diagnosis, invasive and medical treatment of acute myocardial infarction (AMI) lead to a reduction in the mortality rates associated with early and late complications of AMI

  • Our findings show that impaired indices of LV deformation detected two days after successful percutaneous coronary intervention (PCI) for AMI may provide a predictive value in early detection of LV remodelling

  • There were no statistically significant differences between both groups regarding the number of diseased vessels or the infarct related artery (IRA); in the R+ group 50% had the LAD, 16% had the LCX and 33% had the RCA as the IRA, while in the R- group 48% had the LAD, 21% had the LCX and 30% had the RCA as the IRA (Table 2)

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Summary

Introduction

Improvement in the early diagnosis, invasive and medical treatment of acute myocardial infarction (AMI) lead to a reduction in the mortality rates associated with early and late complications of AMI. Left ventricular remodeling is characterized by progressive enlargement and change in the shape of the LV cavity leading to systolic dysfunction. It occurs, as an adaptation to the tissue infarction, as a result of macro and microscopic changes at the cardiomyocyte, leading to structural and functional changes. Left ventricular remodeling is associated with worse outcomes and predisposes to heart failure [2]. Adverse left ventricular remodelling (LVR), defined as progressive ventricular dilatation, distortion of chamber shape, myocardial hypertrophy and deteriorating function, begins in some patients who suffered from acute myocardial infarction (AMI), sometimes even after successful percutaneous coronary intervention (PCI). It could lead to congestive heart failure (CHF) and a poor clinical outcome

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