Abstract
AbstractTwo‐dimensional and deuterium‐induced, differential‐isotope‐shift NMR measurements have made it possible to assign completely all of the 1H and 13C resonances of potassium sucrose octasulfate (K8SOS) and thereby prove complete sulfation of the sugar moiety during synthesis. In addition, a comparison of the 13C NMR chemical shifts obtained for K8SOS and sucralfate made it possible to demonstrate that the sugar moiety in sucralfate is sucrose octasulfate (SOS8−). Finally, deuterium‐induced, differential‐isotope‐shift and 13C NMR techniques were shown to be useful tools for detecting and characterizing carbon‐containing impurities and hydrolysis products in solutions containing SOS8−.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
