Two Different Face of Mastocytoma: Case Report

Abstract

Mastocytosis is a heterogeneous disease group which develops as a result of proliferation of mast cells in different tissues and/or organs or is observed with skin involvement. It is generally observed during childhood and progresses benignly. Mastocytosis may be detected in adults as well; however, the progress is severer and aggressive during adulthood. The most common organ involved is the skin and many organ involvements may also be observed such as bone marrow, liver, gastrointestinal system, spleen and lymph glands. Clinical findings in all disease types depend on the changes caused by release of active editors in granules of the mast cells. A solitary mastocytoma with a diameter of 1-3 cm which is a benign, elastic, infiltrated entity characterized with nodule or plaque with smooth or rough (orange peel) surface may be observed in cutaneous mastocytoma; however, life threatening clinical manifestations characterized with diffuse vesiculobullose lesions may also be detected. In the present study, 2 cases including one case with a benign clinical progress and one case resulted with death are presented. Therefore, it should be kept in mind that mastocytoma cases may progress with bad prognosis and families should be taught to avoid the patient from triggering factors, to apply practical treatment methods by the patient and to follow the patient closely.