Abstract
Two new coordination polymers (CPs), namely [Cu(4-bptzp)(1,3-BDC)]n (1, 1,3-H2BDC = 1,3-benzenedicarboxylic acid, 4-bptzp = 1,4-bis(5-(4-pyridyl)tetrazolyl)propane) and [Co(4-bptzh)(1,3-BDC)]n (2, 4-bptzh = 1,4-bis(5-(4-pyridyl)tetrazolyl)hexane) were prepared by hydrothermal reactions of the corresponding metal salts with the 1,3-H2BDC in the presence of different flexible bis(pyridyl-tetrazole) ligands. The inhibitory effect of compounds 1 and 2 on SK-OV-3 human ovarian cancer cells was assessed. Firstly, the CCK-8 assay was performed and the anti-proliferation activity of compounds 1 and 2 was assessed. Then, the Annexin V-FITC/PI apoptosis assay was performed to detect the apoptosis of the cancer cells in flow cytometry.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
