Abstract
First described together in 1988, S. lugdunensis and S. schleiferi are coagulase-negative Staphylococcus (CNS) species that recently have emerged as potential zoonotic pathogens (Freney et al., 1988). S. lugdunensis typically has been associated with human disease, primarily skin infections and endocarditis, but recently also has been described as an animal pathogen (Frank et al., 2008; Rook et al., 2012). S. schleiferi, which may be coagulase negative (CNS: subsp. schleiferi) or coagulase positive (CPS: subsp. coagulans), typically has been associated with skin infections in dogs and cats, but recently has been described as a human pathogen (Kumar et al., 2007; Tzamalis et al., 2013). In this sense, we apply Calvin Schwabe's definition of zoonosis as “shared infection” of animals and man, without ascribing direction of transmission from one to the other (Schwabe, 1984).
Highlights
While the ubiquitous nature of the genus Staphylococcus generally, and coagulasenegative Staphylococcus (CNS) enhances opportunities for infection, the genetic characteristics of S. lugdunensis and S. schleiferi make them worthy of closer scrutiny
S. lugdunensis and S. schleiferi are examples of CNS often overlooked by routine clinical diagnostic protocols that may be emerging as drug-resistant pathogens
SCCmec IV has been described in clinical isolates of S. schleiferi subsp. coagulans from pets (Roberts et al, 2005)
Summary
While the ubiquitous nature of the genus Staphylococcus generally, and CNS enhances opportunities for infection, the genetic characteristics of S. lugdunensis and S. schleiferi make them worthy of closer scrutiny. Both S. schleiferi and S. lugdunensis have been demonstrated to carry SCCmec elements, and S. schleiferi isolates have been identified recently as multidrug resistant (Roberts et al, 2005; Starlander et al, 2011; Cain, 2013; Penna et al, 2013). Of concern is the propensity for clinical isolates to be methicillin resistant, with many veterinary studies in the last decade reporting rates of 50% or higher (Kania et al, 2004; Bemis et al, 2006; Vanni et al, 2009; Cain et al, 2011a,b; Penna et al, 2013).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
