Abstract
[Co(L1)2(HCOO)] (1) and [Co2(HL2)2(CH3COO)·(NH2)(CH3)] (2) [HL1 = 4-pyridinecarboxylic acid 1-oxide, HL2 = 4-(1H-tetrazol-5-yl)benzoic acid], are new 3D coordination polymers that were successfully obtained via solvothermal conditions as determined by elemental analysis and Fourier transform infrared spectroscopy. Single-crystal diffraction analysis showed that 1 and 2 have 3D porous structures that depend on secondary building units. Furthermore, the application values of the newly developed compounds on radiation pneumonitis were determined, and the corresponding mechanism was examined. First, enzyme-linked immunosorbent assay was performed work to measure the plasma-released inflammatory cytokine content. Then, real-time polymerase chain reaction was used to organize and observe the activation of the AMPK signaling pathway.
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