Two cases of spindle cell lipoma of the bilateral tongue: A case report and literature review

Abstract

Spindle cell lipoma (SCL) is a benign, slow-growing tumor developing from the subcutaneous tissue of the upper back, the posterior neck, or shoulder region, usually occurring in middle-aged or older men as a solitary nodule. However, the involvement of the oral cavity, particularly the tongue, has seldom been reported. SCL is microscopically characterized by a mixture of mature adipocytes and bland spindle cells against a fibromyxoid background. Here, we describe two rare cases of multiple SCLs involving the bilateral margins of the tongue and a literature review. The patients were 72- and 86-year-old Japanese male patients with multiple painless soft nodules on the bilateral margins of the tongue. Excisional biopsy confirmed the diagnosis of SCL, and the tumors were resected. No recurrence was noted at the 12-month follow-up. SCLs of the tongue should be distinguished from other fat-containing spindle cell neoplasms that can develop at this anatomical site.