Two cases of non-cardiac multiple organ abscesses in normal immunocompetent patients and literature review

Abstract

Objective To analyze 2 cases of non-cardiac multi-organ abscesses in normal immunocompentent patients and reviewed the literature, to improve diagnostic capacity of such diseases. Methods 2 cases of non-cardiac multi-organ abscesses in normal immunocompentent patients were analyzed.We searched the Chinese and English database for the keyword of non-cardiac multiple organ abscesses, and reviewed the reports on normal immunocompetent patients. Results A 66-year-old female, complained of intermittent fever for 8 months.She had multiple abscesses in the left shoulder, lungs, L4 and L5 vertebra, and enlarged lymph nodes.Penicilliosis marneffei was found in the pyogenic fluids.With anti-fungal treatment and drainage of the abscess in left shoulder, she got relieved.A 35-year-old male, complained of pharyngalgia, fever and dyspnea for 7 days.He got migration abscesses in the pharynx, neck, mediastinum, and left plural cavity.Streptococcus constellatus and Gemella morbillorum were found in the pyogenic fluid.With antibiotic treatment, drainage of the abscess in the neck and decortications of lung, he recovered.Pathogen infection, tumor, autoimmune diseases, genetic diseases and medicine could present as multiple organ abscesses-like lesions, with pathogen infection as the major cause. Conclusions Accept from pathogen infection, tumor and autoimmune diseases could present as multiple organ abscesses-like lesions in previously normal immunocompetent patients.When patients get no improvement with antibiotics, advanced investigation should be done to exclude tumor, autoimmune diseases, and so on.Investigations of pathogen and pathological examination play an important role in differential diagnosis. Key words: Abscess; Multiple organs; Normal immunocompetent; Non-cardiac