Abstract
BackgroundLate complications and longer-lasting sequelae of COVID-19 infection in adults can occur. Cardiovascular involvement including reduced ejection fraction, coronary artery aneurysms, and pericardial involvement have been reported. Prompt recognition is the first step and secondly, these cardiovascular phenomena require an alternative set of therapeutics from the standard of care for acute COVID-19 infection.Case presentationHere we describe two cases that fulfill the current case definition of the recently defined multisystem inflammatory syndrome in adults (MIS-A). One patient is a 27-year-old white female and the other a 21-year-old French creole male, both without any prior medical history. Both were hospitalized and found to have significant cardiac dysfunction and treated with IVIG, high dose aspirin, and corticosteroids with resolution of their acute illnesses and cardiac sequelae.ConclusionNot only does the immediate impact of this viral infection need to be addressed, but also the long-term complications that could arise if not recognized and treated promptly as seen in our two cases. Patients can develop acute cardiovascular collapse and cardiogenic shock which requires high level of care and treatment within an intensive care unit. Depending on the complications, patients may require treatment for congestive heart failure, pericarditis, or even coronary artery disease acutely with close follow up to ensure improvement or resolution.
Highlights
ConclusionDoes the immediate impact of this viral infection need to be addressed, and the long-term complications that could arise if not recognized and treated promptly as seen in our two cases
The clinical course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in adults is characterized by both upper and lower respiratory tract symptoms and can include pneumonia and acute respiratory distress syndrome
The primary respiratory illness may be absent or mild, with the most severe symptoms manifesting a few weeks after the primary infection as a post infectious inflammatory syndrome called multisystem inflammatory syndrome in children (MIS-C) [1]
Summary
Does the immediate impact of this viral infection need to be addressed, and the long-term complications that could arise if not recognized and treated promptly as seen in our two cases. Patients can develop acute cardiovascular collapse and cardiogenic shock which requires high level of care and treatment within an intensive care unit. Patients may require treatment for congestive heart failure, pericarditis, or even coronary artery disease acutely with close follow up to ensure improvement or resolution
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