Abstract
Mitochondrial diabetes is a refractory type of diabetes mellitus where pancreas beta-cell function attenuates. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) has been reported for pleiotropic effects in addition to effect to glucose tolerance. In animal models, GLP-1RAs were reported to recover mitochondrial function of pancreas beta-cells and increase the growth rate of nerve cells. Our two cases appear to be the first reported cases in the literature of mitochondrial diabetes where GLP-1RAs improved insulin secretion and neuropathy. J Endocrinol Metab. 2019;9(1-2):33-36 doi: https://doi.org/10.14740/jem539
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