Two Cases of Giant Congenital Melanocytic Nevus – A Rare Case Report with Review of Literature

Abstract

Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condition is rare, affecting approximately 1 in every 200,000 to 500,000 births. There is a lifetime risk of 5%–40% for the development of malignant melanoma from the nevus. Early detection of the lesion and regular monitoring are crucial in order to identify any malignant changes. In this report, we present two cases of giant congenital melanocytic nevus, highlighting its rarity, and provide a literature review on the subject.