Abstract
Liposarcomas are rare malignant tumors of adipose tissues with overall incidence of 0.2–0.5% among all the canine neoplasms. They may originate either from bone marrow or extra skeletal sites such as adipose tissues. Histological classification include well differentiated, pleomorphic, and myxoid subtypes. Clinical cytological, gross pathological and histopathological features of two extra skeletal canine liposarcoma cases presented to the Veterinary Teaching Hospital (VTH), University of Peradeniya are described here.
Highlights
Liposarcomas are rare malignant tumors of adipose tissue reported in many animal species, a majority of which are dogs and Shetland Sheepdogs are preferentially affected
Metastasis is rare and when it occurs, usually affects the lung, liver, spleen and bones (Wang et al, 2005).This article describes cytological, gross pathological and histopathological features of two cases of canine liposarcomas presented to the Veterinary Teaching Hospital (VTH), University of Peradeniya
Wide excision of the tumor with safety margins is curative for this type of tumors
Summary
Liposarcomas are rare malignant tumors of adipose tissue reported in many animal species, a majority of which are dogs and Shetland Sheepdogs are preferentially affected (Castro et al, 2014. Wang et al, 2005).The overall incidence of liposarcomas is 0.2–0.5% among all canine neoplasms and the mean age at diagnosis is 9.7 years (Wang et al, 2005). Wang et al, 2005).The overall incidence of liposarcomas is 0.2–0.5% among all canine neoplasms and the mean age at diagnosis is 9.7 years (Wang et al, 2005) These tumors arise de novo and not from pre-existing lipomas or infiltrative lipomas (Wang et al, 2005). Palpation of the limb did not elicit pain but revealed a poorly demarcated, firm tissue growth expanded over the lateral and caudo-medial thigh area (Figure 1:A).Survey radiographs revealed partially encapsulated, mildly radio-dense compressive and expansive sub-cutaneous growth over the lateral thigh. Primary incisions over the left lateral thigh revealed partially encapsulated, poorly demarcated, expansive and infiltrative multiple, yellow-white, variably sized (ranging from 0.2 cm diameter to 1.4 cm diameter), firm and friable masses occupying an extensive sub-cutaneous area (Figure 1: B).
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