Abstract
Recent development of the radioimmunoassay technique has been enabled to measure the low level of serum alphafetoprotein (AFP). A various kinds of malignant tumors, which show elevated serum AFP except hepatic cell carcinomas and embrionic cancers, have been reported. Those are mainly consisted of gastric cancers and cholangiomas, pancreatic and colorectal cancers have been really reported. Prognosis of AFP-producing gastric cancers is poor, because of rapid growing, and easily metastasis of the liver and lymphnodes. Intensive chemotherapy should be recommended for treatment perioperatively. The measurement of serum AFP level may contribute to make diagnosis and to evaluate therapeutic effects. In this report, we emphasize the importance of strict postoperative follow-up, using regular check of serum AFP, CT scan and ultrasonogram.
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