Abstract
Background: Anovulation or inability to produce fertile ovum is an important cause among the women for infertility. One of the formulations given in Bhavaprakasha under Yonirogadhikara, Ashwagandha Kshirpaka, can be effective in Folliculogenesis in females. Objectives: The present study was conducted to compare the efficacy of Ashwagandha kshirpaka & Clomiphene citrate on Folliculogenesis in the management of Vandhyatva. Methods: In present two arm, open labeled randomized standard controlled prospective clinical study, 60 patients suffering with Vandhyatva with anovulatory cycles fulfilling the inclusion and exclusion criteria were selected by purposive sampling technique from the study centre and randomized into two groups. 30 patients in Trial Group received Ashwagandha kshirpaka whereas 30 patients in Control Group 30 patients received Clomiphene citrate. All the patients were subjected to haematological and hormonal profile assay and follicular studies on three consecutive menstrual cycles. Assessment of follicle size & endometrial thickness were done with USG Follicular Study whereas interval between two menstrual cycles & menstrual regulations were assessed and documented in CRF.
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