Abstract

Application of a new investigative strategy to assess genetic and environmental influences on relative body weight. Covariance structure analysis of body mass index (BMI) using genetically informative samples. One-hundred and fourteen monozygotic (MZ) twin pairs (age 5.04-22.93 y), 81 dizygotic (DZ) twin pairs (age 6.05-16.52 y), and 98 virtual twin (VT) pairs, ie same-age unrelated siblings (3.68-54.75 y). Height, weight, BMI variously obtained by direct measurement and self-report. In contrast with most previous studies, significant common environmental influence on BMI was observed. Much past research may have underestimated common environmental effects on BMI because the designs lacked the power or ability to detect them.

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