Abstract
Human Monozygotic (MZ) Twins estimated to occur once in 250 live births, result from an abnormal behavior by embryonic cell(s) to develop as separate embryos. The MZ twins are considered genetically identical and the reduced phenotypic, genetic or chromosomal concordance represents a very important challenge for geneticists. Determination of zygosity by molecular studies usefully provides a superior replacement for the conventional studies of placenta and chorionic membranes. We utilized a protocol based on the CODIS polymorphic markers battery, by using an infrared LI-COR 4200 instrument (LICOR, Nebraska, USA), and we associated the statistical analysis method with formulae derived by the DNA-View's Kinship Module to better evaluate the genetic identity in a group of MZ twins.
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