Abstract
Twin PREGNANCIES, responsible for 1% of births, account for 4 to 10% of all perinatal deaths?. 2 Premature birth appears to be the greatest hazard. Complications of delivery, intrauterine growth retardation, and hemodynamic abnormalities represent additional risks to the twin. 2 Naeye et aP have suggested that the amniotic fluid infection syndrome may be the most common identifiable cause of perinatal death in twins, being implicated in 16 to 38% of twin deaths, depending upon the population studied. Beta hemolytic streptococci, including members of serologic group B, are among tile causes of the syndrome. 4 Group B streptococcal infection in twins has been described, 5-7 but prospective data are lacking. Our prospective studies of GBS infections in infants have been in progress for several years. Data from the first year of investigation, recently reported, ~ included one set of twins who died with fulminant GBS sepsis. Additional cases, septicemia in a mother and one of her twin infants, prompted this analysis of the outcome of twin pregnancies in this population. An increased risk of GBS !nfection in twin pregnancies was strikingly evident.
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