Twin Peaks? No Evidence of Bimodal Distribution of Outcomes in Clinical Trials of Nonsurgical Interventions for Spinal Pain: An Exploratory Analysis.

Neil E O'Connell,Matthew L Stevens,Qiang Li,Steven J Kamper

doi:10.1016/j.jpain.2017.03.004

Twin Peaks? No Evidence of Bimodal Distribution of Outcomes in Clinical Trials of Nonsurgical Interventions for Spinal Pain: An Exploratory Analysis.

Neil E O'Connell, Matthew L Stevens + Show 2 more

Open Access

https://doi.org/10.1016/j.jpain.2017.03.004

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Journal: The journal of pain	Publication Date: Mar 25, 2017
Citations: 7	License type: cc-by-nc-nd

Affiliation: The George Institute for Global Health, University of Sydney, Brunel University London

#Bimodal Distribution #Bimodally Distributed + Show 8 more

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Abstract

Secondary analysis of clinical trials of nonsurgical interventions for spinal pain found no evidence for bimodally distributed outcomes. The findings do not support the automatic prioritization of responder analyses over the average between group difference in the evaluation of treatment effectiveness for spinal pain.

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