Abstract

Objective: To assess prevalences of diabetes mellitus type 2 (T2DM), hypertension and hypercholesterolemia across BMI categories during 20 years of aging among Swedish men. Design and Method: The longitudinal population-based cohort Uppsala Longitudinal Study of Adult Men (initially 2322 50-year-old men) was used. Weight, height, blood pressure, total cholesterol and plasma glucose were measured at ages 50, 60 and 70. Results: The prevalences of overweight (BMI 25–29.9 kg/m2) were 47%, 52% and 63% at 50, 60, and 70 years of age. At the same ages the prevalences of obesity (BMI≥30) were 7%, 9% and 13% respectively. The corresponding prevalences of T2DM were 5%, 6% and 11%; hypertension 42%, 68% and 72%; and hypercholesterolemia 95%, 91% and 81%. The prevalence of T2DM was higher with higher BMI categories at each age: 4/5/5% of normal weight, 4/5/12% of overweight and 13/16/23% of obese men, at 50, 60 and 70 years of age, respectively. Hypertension followed a similar pattern with 33/62/67% (normal weight), 49/75/77% (overweight) and 75/85/86% (obese). Prevalence of hypercholesterolemia was not related to BMI group at any age. Conclusions: An approximate doubling of the prevalences of obesity, diabetes and hypertension was observed over 20 years of aging among Swedish men. The significance of overweight and obesity for the prevalence of diabetes and hypertension appears to persist with increasing age.

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