Abstract
A malonohydrazide derivative bearing an imine and phenolic group was synthesized and had a high affinity and selectivity towards Zn2+. The recognition properties of receptor 1 were evaluated using absorbance and fluorescence spectroscopy. The 1:1 stoichiometry of 1.Zn2+ was confirmed from job׳s plot, mass spectra and density functional theory (DFT). The detection of Zn2+ in intracellular environment of HeLa cell through confocal microscopy was successfully applied for live cell imaging.
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