Abstract
An eco-friendly green synthetic procedure was accomplished through the one-pot three-component synthesis of α-aminophosphonates having –CF3 moiety in good to excellent yields, under ultrasonication and solvent-free conditions in the presence of tungstosulfonic acid as an efficient, reusable, heterogeneous solid acid catalyst. All the title compounds were evaluated for their antioxidant activity using DPPH, H2O2 methods and antimicrobial activity by disc diffusion method. The bio-activity revealed that all the title compounds showed significant antioxidant and antimicrobial activities.
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